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The Role of RhoA and Cytoskeleton in Myofibroblast Transformation in Hyperoxic Lung Fibrosis

Myofibroblast transformation is a key process in the pathogenesis of lung fibrosis. We have previously reported that hyperoxia induces RhoA activation in HFL-1 lung fibroblasts and RhoA mediates collagen synthesis in hyperoxic lung fibrosis. In the present study, we investigated the role of RhoA and...

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Autors principals: Ni, Jixiang, Dong, Zheng, Han, Weihong, Kondrikov, Dmitry, Su, Yunchao
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849210/
https://ncbi.nlm.nih.gov/pubmed/23517783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2013.03.012
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