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Heat Shock Protein 70 Prevents Hyperoxia-Induced Disruption of Lung Endothelial Barrier via Caspase-Dependent and AIF-Dependent Pathways

Exposure of pulmonary artery endothelial cells (PAECs) to hyperoxia results in a compromise in endothelial monolayer integrity, an increase in caspase-3 activity, and nuclear translocation of apoptosis-inducing factor (AIF), a marker of caspase-independent apoptosis. In an endeavor to identify prote...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kondrikov, Dmitry, Fulton, David, Dong, Zheng, Su, Yunchao
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465980/
https://ncbi.nlm.nih.gov/pubmed/26066050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129343
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