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Novel Peptide for Attenuation of Hyperoxia-induced Disruption of Lung Endothelial Barrier and Pulmonary Edema via Modulating Peroxynitrite Formation

Pulmonary damages of oxygen toxicity include vascular leakage and pulmonary edema. We have previously reported that hyperoxia increases the formation of NO and peroxynitrite in lung endothelial cells via increased interaction of endothelial nitric oxide (eNOS) with β-actin. A peptide (P326TAT) with...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kondrikov, Dmitry, Gross, Christine, Black, Stephen M., Su, Yunchao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246092/
https://ncbi.nlm.nih.gov/pubmed/25315770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.585356
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