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Splicing fidelity: DEAD/H-box ATPases as molecular clocks

The spliceosome discriminates against suboptimal substrates, both during assembly and catalysis, thereby enhancing specificity during pre-mRNA splicing. Central to such fidelity mechanisms are a conserved subset of the DEAD- and DEAH-box ATPases, which belong to a superfamily of proteins that mediat...

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Hlavní autoři: Koodathingal, Prakash, Staley, Jonathan P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849154/
https://ncbi.nlm.nih.gov/pubmed/23770752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.25245
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