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Splicing fidelity: DEAD/H-box ATPases as molecular clocks
The spliceosome discriminates against suboptimal substrates, both during assembly and catalysis, thereby enhancing specificity during pre-mRNA splicing. Central to such fidelity mechanisms are a conserved subset of the DEAD- and DEAH-box ATPases, which belong to a superfamily of proteins that mediat...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3849154/ https://ncbi.nlm.nih.gov/pubmed/23770752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.25245 |
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