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Co-Transplantation of GDNF-Overexpressing Neural Stem Cells and Fetal Dopaminergic Neurons Mitigates Motor Symptoms in a Rat Model of Parkinson’s Disease

Striatal transplantation of dopaminergic (DA) neurons or neural stem cells (NSCs) has been reported to improve the symptoms of Parkinson’s disease (PD), but the low rate of cell survival, differentiation, and integration in the host brain limits the therapeutic efficacy. We investigated the therapeu...

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Main Authors: Deng, Xingli, Liang, Yuanxin, Lu, Hua, Yang, Zhiyong, Liu, Ru’en, Wang, Jinkun, Song, Xiaobin, Long, Jiang, Li, Yu, Lei, Deqiang, Feng, Zhongtang
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849044/
https://ncbi.nlm.nih.gov/pubmed/24312503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080880
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