Co-Transplantation of GDNF-Overexpressing Neural Stem Cells and Fetal Dopaminergic Neurons Mitigates Motor Symptoms in a Rat Model of Parkinson’s Disease

Striatal transplantation of dopaminergic (DA) neurons or neural stem cells (NSCs) has been reported to improve the symptoms of Parkinson’s disease (PD), but the low rate of cell survival, differentiation, and integration in the host brain limits the therapeutic efficacy. We investigated the therapeu...

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Detalhes bibliográficos
Main Authors: Deng, Xingli, Liang, Yuanxin, Lu, Hua, Yang, Zhiyong, Liu, Ru’en, Wang, Jinkun, Song, Xiaobin, Long, Jiang, Li, Yu, Lei, Deqiang, Feng, Zhongtang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849044/
https://ncbi.nlm.nih.gov/pubmed/24312503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080880
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