The PKR activator, PACT, becomes a PKR inhibitor during HIV-1 replication

BACKGROUND: HIV-1 translation is modulated by the activation of the interferon (IFN)-inducible Protein Kinase RNA-activated (PKR). PKR phosphorylates its downstream targets, including the alpha subunit of the eukaryotic translation Initiation Factor 2 (eIF2α), which decreases viral replication. The...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Clerzius, Guerline, Shaw, Eileen, Daher, Aïcha, Burugu, Samantha, Gélinas, Jean-François, Ear, Thornin, Sinck, Lucile, Routy, Jean-Pierre, Mouland, Andrew J, Patel, Rekha C, Gatignol, Anne
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2013
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3848765/
https://ncbi.nlm.nih.gov/pubmed/24020926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-96
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk