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Enhancement of Replication of RNA Viruses by ADAR1 via RNA Editing and Inhibition of RNA-Activated Protein Kinase

Adenosine deaminase acting on RNA 1 (ADAR1) is a double-stranded RNA binding protein and RNA-editing enzyme that modifies cellular and viral RNAs, including coding and noncoding RNAs. This interferon (IFN)-induced protein was expected to have an antiviral role, but recent studies have demonstrated t...

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Hlavní autoři: Gélinas, Jean-François, Clerzius, Guerline, Shaw, Eileen, Gatignol, Anne
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165853/
https://ncbi.nlm.nih.gov/pubmed/21490091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00240-11
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