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Mutation Spectra of S-(2-Hydroxy-3,4-epoxybutyl)glutathione: Comparison with 1,3-Butadiene and Its Metabolites in the Escherichia coli rpoB gene
S-(2-Hydroxy-3,4-epoxybutyl)glutathione (DEB-GSH conjugate) is formed from the reaction of 1,2:3,4-diepoxybutane (DEB) with glutathione (GSH), and the conjugate is considerably more mutagenic than several other butadiene-derived epoxides—including DEB—in Salmonella typhimurium TA1535 (Cho, S-H. et a...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3848527/ https://ncbi.nlm.nih.gov/pubmed/22670845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx3002109 |
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