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Replication Past the Butadiene Diepoxide-derived DNA Adduct S-[4-(N(6)-Deoxyadenosinyl)2,3-dihydroxybutyl]glutathione by DNA Polymerases
1,2,3,4-Diepoxybutane (DEB), a metabolite of the carcinogen butadiene, has been shown to cause glutathione (GSH)-dependent base-substitution mutations, especially A:T to G:C in Salmonella typhimurium TA1535 (Chem. Res. Toxicol. 23, 1544 (2010)) and Escherichia coli TRG8 cells (Chem. Res. Toxicol. 25...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4049171/ https://ncbi.nlm.nih.gov/pubmed/23701509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx400145e |
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