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Partial loss of Smad signaling during in vitro progression of HPV16-immortalized human keratinocytes
BACKGROUND: Disruption of the transforming growth factor-beta (TGF-β) signaling pathway is observed in many cancers, including cervical cancer, resulting in TGF-β resistance. While normal human keratinocytes (HKc) and human papillomavirus type 16-immortalized HKc (HKc/HPV16) are sensitive to the gro...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3848426/ https://ncbi.nlm.nih.gov/pubmed/24047375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-424 |
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