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HPV16-transformed human keratinocytes depend on SIX1 expression for proliferation and HPV E6/E7 gene expression
The homeodomain transcription factor SIX1 plays a critical role in embryogenesis, is not expressed in normal adult tissue, but is expressed in many malignancies, including cervical cancer. SIX1 drives the progression of HPV16-immortalized human keratinocytes (HKc/HPV16) toward malignancy: HKc/HPV16...
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| Veröffentlicht in: | Virology |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6901751/ https://ncbi.nlm.nih.gov/pubmed/31425971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2019.08.009 |
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