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TGF-β Regulation of Gene Expression at Early and Late Stages of HPV16-Mediated Transformation of Human Keratinocytes

In our in vitro model for HPV16-mediated transformation, HPV16-immortalized human keratinocytes (HKc/HPV16) give rise to differentiation resistant, premalignant cells (HKc/DR). HKc/DR, but not HKc/HPV16, are resistant to growth inhibition by transforming growth factor beta (TGF-β), due to a partial...

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Bibliografiske detaljer
Main Authors: Kowli, Sangeeta, Velidandla, Rupa, Creek, Kim E., Pirisi, Lucia
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895483/
https://ncbi.nlm.nih.gov/pubmed/24210100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.08.034
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