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Investigations of Homologous Recombination Pathways and Their Regulation

The DNA double-strand break (DSB), arising from exposure to ionizing radiation or various chemotherapeutic agents or from replication fork collapse, is among the most dangerous of chromosomal lesions. DSBs are highly cytotoxic and can lead to translocations, deletions, duplications, or mutations if...

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Main Authors: Daley, James M., Kwon, YoungHo, Niu, Hengyao, Sung, Patrick
Format: Artigo
Jezik:Inglês
Izdano: YJBM 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3848099/
https://ncbi.nlm.nih.gov/pubmed/24348209
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