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Reconstituted System for the Examination of DNA Repair Synthesis in Homologous Recombination
In homologous recombination (HR), DNA polymerase δ-mediated DNA synthesis occurs within the displacement loop (D-loop) that is made by the recombinase Rad51 in conjunction with accessory factors. We describe in this article the reconstitution of the D-loop and repair DNA synthesis reactions using pu...
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| Опубликовано в: : | Methods Enzymol |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5823693/ https://ncbi.nlm.nih.gov/pubmed/28645374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2017.03.021 |
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