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Investigations of Homologous Recombination Pathways and Their Regulation

The DNA double-strand break (DSB), arising from exposure to ionizing radiation or various chemotherapeutic agents or from replication fork collapse, is among the most dangerous of chromosomal lesions. DSBs are highly cytotoxic and can lead to translocations, deletions, duplications, or mutations if...

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Detalhes bibliográficos
Main Authors: Daley, James M., Kwon, YoungHo, Niu, Hengyao, Sung, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: YJBM 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3848099/
https://ncbi.nlm.nih.gov/pubmed/24348209
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