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DNA sequence alignment by microhomology sampling during homologous recombination

Homologous recombination (HR) mediates the exchange of genetic information between sister or homologous chromatids. During HR, members of the RecA/Rad51 family of recombinases must somehow search through vast quantities of DNA sequence to align and pair ssDNA with a homologous dsDNA template. Here w...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Qi, Zhi, Redding, Sy, Lee, Ja Yil, Gibb, Bryan, Kwon, YoungHo, Niu, Hengyao, Gaines, William A., Sung, Patrick, Greene, Eric C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344887/
https://ncbi.nlm.nih.gov/pubmed/25684365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.01.029
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