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Rad54 Drives ATP Hydrolysis-Dependent DNA Sequence Alignment during Homologous Recombination
Homologous recombination (HR) helps maintain genome integrity, and HR defects give rise to disease, especially cancer. During HR, damaged DNA must be aligned with an undamaged template through a process referred to as the homology search. Despite decades of study, key aspects of this search remain u...
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| Veröffentlicht in: | Cell |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7418177/ https://ncbi.nlm.nih.gov/pubmed/32502392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.04.056 |
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