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Rad54 Drives ATP Hydrolysis-Dependent DNA Sequence Alignment during Homologous Recombination

Homologous recombination (HR) helps maintain genome integrity, and HR defects give rise to disease, especially cancer. During HR, damaged DNA must be aligned with an undamaged template through a process referred to as the homology search. Despite decades of study, key aspects of this search remain u...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Crickard, J. Brooks, Moevus, Corentin J., Kwon, Youngho, Sung, Patrick, Greene, Eric C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7418177/
https://ncbi.nlm.nih.gov/pubmed/32502392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.04.056
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