A Simple and Effective Method to Generate Lentiviral Vectors for Ex Vivo Gene Delivery to Mature Human Peripheral Blood Lymphocytes

Human ex vivo gene therapy protocols have been used successfully to treat a variety of genetic disorders, infectious diseases, and cancer. Murine oncoretroviruses (specifically, gammaretroviruses) have served as the primary gene delivery vehicles for these trials. However, in some cases, such vector...

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Autors principals: Yang, Shicheng, Karne, Neel K., Goff, Stephanie L., Black, Mary A., Xu, Hui, Bischof, Daniela, Cornetta, Kenneth, Rosenberg, Steven A., Morgan, Richard A., Feldman, Steven A.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2012
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847989/
https://ncbi.nlm.nih.gov/pubmed/22515320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2011.199
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