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RNA-Seq analysis to capture the transcriptome landscape of a single cell

We describe here a protocol for digital transcriptome analysis in a single mouse blastomere using a deep sequencing approach. An individual blastomere was first isolated and put into lysate buffer by mouth pipette. Reverse transcription was then performed directly on the whole cell lysate. After thi...

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Hlavní autoři: Tang, Fuchou, Barbacioru, Catalin, Nordman, Ellen, Xu, Nanlan, Bashkirov, Vladimir I, Lao, Kaiqin, Surani, M. Azim
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847604/
https://ncbi.nlm.nih.gov/pubmed/20203668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2009.236
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