Deterministic and Stochastic Allele Specific Gene Expression in Single Mouse Blastomeres

Stochastic and deterministic allele specific gene expression (ASE) might influence single cell phenotype, but the extent and nature of the phenomenon at the onset of early mouse development is unknown. Here we performed single cell RNA-Seq analysis of single blastomeres of mouse embryos, which revea...

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Bibliografiske detaljer
Main Authors: Tang, Fuchou, Barbacioru, Catalin, Nordman, Ellen, Bao, Siqin, Lee, Caroline, Wang, Xiaohui, Tuch, Brian B., Heard, Edith, Lao, Kaiqin, Surani, M. Azim
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121735/
https://ncbi.nlm.nih.gov/pubmed/21731673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021208
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