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rAAV-mediated overexpression of TGF-β stably restructures human osteoarthritic articular cartilage in situ

BACKGROUND: Therapeutic gene transfer is of significant value to elaborate efficient, durable treatments against human osteoarthritis (OA), a slow, progressive, and irreversible disorder for which there is no cure to date. METHODS: Here, we directly applied a recombinant adeno-associated virus (rAAV...

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書誌詳細
主要な著者: Venkatesan, Jagadeesh K, Rey-Rico, Ana, Schmitt, Gertrud, Wezel, Anna, Madry, Henning, Cucchiarini, Magali
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847562/
https://ncbi.nlm.nih.gov/pubmed/24034904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-11-211
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