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The dopamine D(1) receptor is expressed and facilitates relaxation in airway smooth muscle
BACKGROUND: Dopamine signaling is mediated by G(s) protein-coupled “D(1)-like” receptors (D(1) and D(5)) and G(i)-coupled “D(2)-like” receptors (D(2-4)). In asthmatic patients, inhaled dopamine induces bronchodilation. Although the G(i)-coupled dopamine D(2) receptor is expressed and sensitizes aden...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3847358/ https://ncbi.nlm.nih.gov/pubmed/24004608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-14-89 |
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