Novel identification of the free fatty acid receptor FFAR1 that promotes contraction in airway smooth muscle

Obesity is one of the major risk factors for asthma. Previous studies have demonstrated that free fatty acid levels are elevated in the plasma of obese individuals. Medium- and long-chain free fatty acids act as endogenous ligands for the free fatty acid receptors FFAR1/GPR40 and FFAR4/GPR120, which...

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Vydáno v:Am J Physiol Lung Cell Mol Physiol
Hlavní autoři: Mizuta, Kentaro, Zhang, Yi, Mizuta, Fumiko, Hoshijima, Hiroshi, Shiga, Toshiya, Masaki, Eiji, Emala, Charles W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628981/
https://ncbi.nlm.nih.gov/pubmed/26342087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00041.2015
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