Novel identification of the free fatty acid receptor FFAR1 that promotes contraction in airway smooth muscle

Obesity is one of the major risk factors for asthma. Previous studies have demonstrated that free fatty acid levels are elevated in the plasma of obese individuals. Medium- and long-chain free fatty acids act as endogenous ligands for the free fatty acid receptors FFAR1/GPR40 and FFAR4/GPR120, which...

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Publicado en:Am J Physiol Lung Cell Mol Physiol
Main Authors: Mizuta, Kentaro, Zhang, Yi, Mizuta, Fumiko, Hoshijima, Hiroshi, Shiga, Toshiya, Masaki, Eiji, Emala, Charles W.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628981/
https://ncbi.nlm.nih.gov/pubmed/26342087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00041.2015
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