Nanoparticle-mediated catalase delivery protects human neurons from oxidative stress

Several neurodegenerative diseases and brain injury involve reactive oxygen species and implicate oxidative stress in disease mechanisms. Hydrogen peroxide (H(2)O(2)) formation due to mitochondrial superoxide leakage perpetuates oxidative stress in neuronal injury. Catalase, an H(2)O(2)-degrading en...

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Bibliografske podrobnosti
Main Authors: Singhal, A, Morris, V B, Labhasetwar, V, Ghorpade, A
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2013
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847304/
https://ncbi.nlm.nih.gov/pubmed/24201802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.362
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