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Nanoparticle-mediated catalase delivery protects human neurons from oxidative stress

Several neurodegenerative diseases and brain injury involve reactive oxygen species and implicate oxidative stress in disease mechanisms. Hydrogen peroxide (H(2)O(2)) formation due to mitochondrial superoxide leakage perpetuates oxidative stress in neuronal injury. Catalase, an H(2)O(2)-degrading en...

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Detalhes bibliográficos
Main Authors: Singhal, A, Morris, V B, Labhasetwar, V, Ghorpade, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847304/
https://ncbi.nlm.nih.gov/pubmed/24201802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.362
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