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Adenovirus-Mediated Delivery of Catalase to Retinal Pigment Epithelial Cells Protects Neighboring Photoreceptors from Photo-Oxidative Stress

Oxidative stress is involved in the pathogenesis of many diseases. Overexpression of antioxidant enzymes by gene therapy may protect tissues from oxidative damage. Because the reactive oxygen species hydrogen peroxide can diffuse across cell membranes, we hypothesized that overexpression of the anti...

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Detalhes bibliográficos
Main Authors: Rex, T.S., Tsui, I., Hahn, P., Maguire, A.M., Duan, D., Bennett, J., Dunaief, J.L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118285/
https://ncbi.nlm.nih.gov/pubmed/15585111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2004.15.960
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