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Ataxin 1, a SCA1 neurodegenerative disorder protein, is functionally linked to the silencing mediator of retinoid and thyroid hormone receptors

Ataxin 1 (Atx1) is a foci-forming polyglutamine protein of unknown function, whose mutant form causes type 1 spinocerebellar ataxia in humans and exerts neurotoxicity in transgenic mouse and fly expressing mutant Atx1. In this study, we demonstrate that Atx1 interacts with the transcriptional corepr...

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Autors principals: Tsai, Chih-Cheng, Kao, Hung-Ying, Mitzutani, Akifumi, Banayo, Ester, Rajan, Harini, McKeown, Michael, Evans, Ronald M.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC384693/
https://ncbi.nlm.nih.gov/pubmed/15016912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400615101
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