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Boat, an AXH domain protein, suppresses the cytotoxicity of mutant ataxin-1

Ataxin-1 is a neurodegenerative disorder protein whose glutamine-repeat expanded form causes spinocerebellar ataxia type 1 (SCA1) in humans and exerts cytotoxicity in Drosophila and mouse. We report here that the cytotoxicity caused by ataxin-1 is modulated by association with a related protein, Bro...

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Detalhes bibliográficos
Main Authors: Mizutani, Akifumi, Wang, Lei, Rajan, Harini, Vig, Parminder J S, Alaynick, William A, Thaler, Joshua P, Tsai, Chih-Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224676/
https://ncbi.nlm.nih.gov/pubmed/16121196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600785
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