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Mice with RyR1 mutation (Y524S) undergo hypermetabolic response to simvastatin
BACKGROUND: Statins are widely used drugs for the treatment of hyperlipidemia. Though relatively safe, some individuals taking statins experience rhabdymyolysis, muscle pain, and cramping, a condition termed statin-induced myopathy (SIM). To determine if mutations in the skeletal muscle calcium (Ca(...
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| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
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BioMed Central
2013
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3846650/ https://ncbi.nlm.nih.gov/pubmed/24004537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2044-5040-3-22 |
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