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Mice with RyR1 mutation (Y524S) undergo hypermetabolic response to simvastatin
BACKGROUND: Statins are widely used drugs for the treatment of hyperlipidemia. Though relatively safe, some individuals taking statins experience rhabdymyolysis, muscle pain, and cramping, a condition termed statin-induced myopathy (SIM). To determine if mutations in the skeletal muscle calcium (Ca(...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3846650/ https://ncbi.nlm.nih.gov/pubmed/24004537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2044-5040-3-22 |
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