Phosphorylation of the amino-terminal region of X11L regulates its interaction with APP

X11-like (X11L) is neuronal adaptor protein that interacts with the amyloid β-protein precursor (APP) and regulates its metabolism. The phosphotyrosine interaction/binding (PI/PTB) domain of X11L interacts with the cytoplasmic region of APP695. We found that X11L-APP interaction is enhanced in osmot...

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Detalhes bibliográficos
Main Authors: Sakuma, Megumi, Tanaka, Emi, Taru, Hidenori, Tomita, Susumu, Gandy, Sam, Nairn, Angus C., Nakaya, Tadashi, Yamamoto, Tohru, Suzuki, Toshiharu
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846477/
https://ncbi.nlm.nih.gov/pubmed/19222704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.05988.x
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