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Mechanism of Cd(2+)-coordination during Slow Inactivation in Potassium Channels
In K(+) channels, rearrangements of the pore outer-vestibule have been associated with C-type inactivation gating. Paradoxically, the crystal structure of Open/C-type inactivated KcsA suggest these movements to be modest in magnitude. Here, we show that under physiological conditions, the KcsA outer...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3846092/ https://ncbi.nlm.nih.gov/pubmed/22771214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.03.027 |
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