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Targeting the PI3K-AKT-mTOR signaling network in cancer

The phosphoinositide 3-kinase-AKT-mammalian target of rapamycin (PI3K-AKT-mTOR) pathway is a frequently hyperactivated pathway in cancer and is important for tumor cell growth and survival. The development of targeted therapies against mTOR, a vital substrate along this pathway, led to the approval...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Khan, Khurum H., Yap, Timothy A., Yan, Li, Cunningham, David
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Sun Yat-sen University Cancer Center 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845556/
https://ncbi.nlm.nih.gov/pubmed/23642907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5732/cjc.013.10057
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