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Distinct structural alterations in PCNA block DNA mismatch repair

During DNA replication, mismatches and small loops in the DNA resulting from insertions or deletions are repaired by the mismatch repair (MMR) machinery. Proliferating cell nuclear antigen (PCNA) plays an important role in both mismatch-recognition and resynthesis stages of MMR. Previously, two muta...

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Detalhes bibliográficos
Main Authors: Dieckman, Lynne M., Boehm, Elizabeth M., Hingorani, Manju M., Washington, M. Todd
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845532/
https://ncbi.nlm.nih.gov/pubmed/23869605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400378e
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