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Distinct structural alterations in PCNA block DNA mismatch repair

During DNA replication, mismatches and small loops in the DNA resulting from insertions or deletions are repaired by the mismatch repair (MMR) machinery. Proliferating cell nuclear antigen (PCNA) plays an important role in both mismatch-recognition and resynthesis stages of MMR. Previously, two muta...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dieckman, Lynne M., Boehm, Elizabeth M., Hingorani, Manju M., Washington, M. Todd
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845532/
https://ncbi.nlm.nih.gov/pubmed/23869605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400378e
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