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ER Dysfunction and Protein Folding Stress in ALS

Amyotrophic lateral sclerosis (ALS) is the most frequent paralytic disease in adults. Most ALS cases are considered sporadic with no clear genetic component. The disruption of protein homeostasis due to chronic stress responses at the endoplasmic reticulum (ER) and the accumulation of abnormal prote...

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Bibliografiske detaljer
Main Authors: Matus, Soledad, Valenzuela, Vicente, Medinas, Danilo B., Hetz, Claudio
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845333/
https://ncbi.nlm.nih.gov/pubmed/24324498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/674751
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