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ER Dysfunction and Protein Folding Stress in ALS
Amyotrophic lateral sclerosis (ALS) is the most frequent paralytic disease in adults. Most ALS cases are considered sporadic with no clear genetic component. The disruption of protein homeostasis due to chronic stress responses at the endoplasmic reticulum (ER) and the accumulation of abnormal prote...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Hindawi Publishing Corporation
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3845333/ https://ncbi.nlm.nih.gov/pubmed/24324498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/674751 |
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