Serotonin regulates glucose-stimulated insulin secretion from pancreatic β cells during pregnancy

In preparation for the metabolic demands of pregnancy, β cells in the maternal pancreatic islets increase both in number and in glucose-stimulated insulin secretion (GSIS) per cell. Mechanisms have been proposed for the increased β cell mass, but not for the increased GSIS. Because serotonin product...

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Main Authors: Ohara-Imaizumi, Mica, Kim, Hail, Yoshida, Masashi, Fujiwara, Tomonori, Aoyagi, Kyota, Toyofuku, Yukiko, Nakamichi, Yoko, Nishiwaki, Chiyono, Okamura, Tadashi, Uchida, Toyoyoshi, Fujitani, Yoshio, Akagawa, Kimio, Kakei, Masafumi, Watada, Hirotaka, German, Michael S., Nagamatsu, Shinya
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2013
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845121/
https://ncbi.nlm.nih.gov/pubmed/24218571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310953110
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