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Crystal structure of the human eIF4AIII–CWC22 complex shows how a DEAD-box protein is inhibited by a MIF4G domain

DEAD-box proteins are involved in all aspects of RNA processing. They bind RNA in an ATP-dependent manner and couple ATP hydrolysis to structural and compositional rearrangements of ribonucleoprotein particles. Conformational control is a major point of regulation for DEAD-box proteins to act on app...

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Detalhes bibliográficos
Main Authors: Buchwald, Gretel, Schüssler, Steffen, Basquin, Claire, Le Hir, Hervé, Conti, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845097/
https://ncbi.nlm.nih.gov/pubmed/24218557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1314684110
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