Isoflurane-Induced Caspase-3 Activation Is Dependent on Cytosolic Calcium and Can Be Attenuated by Memantine

Increasing evidence indicates that caspase activation and apoptosis are associated with a variety of neurodegenerative disorders, including Alzheimer's disease. We reported that anesthetic isoflurane can induce apoptosis, alter processing of the amyloid precursor protein (APP), and increase amy...

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Главные авторы: Zhang, Guohua, Dong, Yuanlin, Zhang, Bin, Ichinose, Fumito, Wu, Xu, Culley, Deborah J., Crosby, Gregory, Tanzi, Rudolph E., Xie, Zhongcong
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844798/
https://ncbi.nlm.nih.gov/pubmed/18434534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5694-07.2008
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