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Vitamin C attenuates isoflurane-induced caspase-3 activation and cognitive impairment

BACKGROUND: Anesthetic isoflurane has been reported to induce caspase-3 activation. The underlying mechanism(s) and targeted intervention(s), however, remain largely to be determined. Vitamin C (VitC) inhibits oxidative stress and apoptosis. We therefore employed VitC to further determine the up-str...

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Detalhes bibliográficos
Publicado no:Mol Neurobiol
Main Authors: Cheng, Baiqi, Zhang, Yiying, Wang, Arthur, Dong, Yuanlin, Xie, Zhongcong
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418956/
https://ncbi.nlm.nih.gov/pubmed/25367886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-014-8959-3
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