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Anesthetic Propofol Attenuates the Isoflurane-Induced Caspase-3 Activation and Aβ Oligomerization

Accumulation and deposition of β-amyloid protein (Aβ) are the hallmark features of Alzheimer's disease. The inhalation anesthetic isoflurane has been shown to induce caspase activation and increase Aβ accumulation. In addition, recent studies suggest that isoflurane may directly promote the for...

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Detalhes bibliográficos
Main Authors: Zhang, Yiying, Zhen, Yu, Dong, Yuanlin, Xu, Zhipeng, Yue, Yun, Golde, Todd E., Tanzi, Rudolph E., Moir, Robert D., Xie, Zhongcong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206055/
https://ncbi.nlm.nih.gov/pubmed/22069482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027019
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