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Anesthetic Propofol Attenuates the Isoflurane-Induced Caspase-3 Activation and Aβ Oligomerization

Accumulation and deposition of β-amyloid protein (Aβ) are the hallmark features of Alzheimer's disease. The inhalation anesthetic isoflurane has been shown to induce caspase activation and increase Aβ accumulation. In addition, recent studies suggest that isoflurane may directly promote the for...

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Autores principales: Zhang, Yiying, Zhen, Yu, Dong, Yuanlin, Xu, Zhipeng, Yue, Yun, Golde, Todd E., Tanzi, Rudolph E., Moir, Robert D., Xie, Zhongcong
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206055/
https://ncbi.nlm.nih.gov/pubmed/22069482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027019
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