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Anesthetic Propofol Attenuates the Isoflurane-Induced Caspase-3 Activation and Aβ Oligomerization

Accumulation and deposition of β-amyloid protein (Aβ) are the hallmark features of Alzheimer's disease. The inhalation anesthetic isoflurane has been shown to induce caspase activation and increase Aβ accumulation. In addition, recent studies suggest that isoflurane may directly promote the for...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Yiying, Zhen, Yu, Dong, Yuanlin, Xu, Zhipeng, Yue, Yun, Golde, Todd E., Tanzi, Rudolph E., Moir, Robert D., Xie, Zhongcong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206055/
https://ncbi.nlm.nih.gov/pubmed/22069482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027019
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