Effects of the sazetidine-a family of compounds on the body temperature in wildtype, nicotinic receptor β2(−/−) and α7(−/−) mice

Nicotine elicits hypothermic responses in rodents. This effect appears to be related to nicotinic receptor desensitization because sazetidine-A, an α4β2 nicotinic receptor desensitizing agent, produces marked hypothermia and potentiates nicotine-induced hypothermia in mice. To determine the specific...

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Main Authors: Levin, Edward D., Sexton, Hannah G., Gordon, Karen, Gordon, Christopher J., Xiao, Yingxian, Kellar, Kenneth J., Yenugonda, Venkata Mahidhar, Liu, Yong, White, Michael P., Paige, Mikell, Brown, Milton L., Rezvani, Amir H.
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844546/
https://ncbi.nlm.nih.gov/pubmed/24036108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2013.08.037
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