Skeletal Muscle-Specific CPT1 Deficiency Elevates Lipotoxic Intermediates but Preserves Insulin Sensitivity

Objective. By specific knockout of carnitine palmitoyl transferase 1b (CPT1b) in skeletal muscles, we explored the effect of CPT1b deficiency on lipids and insulin sensitivity. Methods. Mice with specific knockout of CPT1b in skeletal muscles (CPT1b M−/−) were used for the experiment group, with lit...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Shi, Wanchun, Hu, Siping, Wang, Wenhua, Zhou, Xiaohui, Qiu, Wei
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Hindawi Publishing Corporation 2013
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844227/
https://ncbi.nlm.nih.gov/pubmed/24319696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/163062
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