Perilipin 2 Improves Insulin Sensitivity in Skeletal Muscle Despite Elevated Intramuscular Lipid Levels

Type 2 diabetes is characterized by excessive lipid storage in skeletal muscle. Excessive intramyocellular lipid (IMCL) storage exceeds intracellular needs and induces lipotoxic events, ultimately contributing to the development of insulin resistance. Lipid droplet (LD)–coating proteins may control...

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Bibliografiset tiedot
Päätekijät: Bosma, Madeleen, Hesselink, Matthijs K.C., Sparks, Lauren M., Timmers, Silvie, Ferraz, Maria João, Mattijssen, Frits, van Beurden, Denis, Schaart, Gert, de Baets, Marc H., Verheyen, Fons K., Kersten, Sander, Schrauwen, Patrick
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Diabetes Association 2012
Aiheet:
Metabolism
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478528/
https://ncbi.nlm.nih.gov/pubmed/22807032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1402
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