Perilipin 2 Improves Insulin Sensitivity in Skeletal Muscle Despite Elevated Intramuscular Lipid Levels

Type 2 diabetes is characterized by excessive lipid storage in skeletal muscle. Excessive intramyocellular lipid (IMCL) storage exceeds intracellular needs and induces lipotoxic events, ultimately contributing to the development of insulin resistance. Lipid droplet (LD)–coating proteins may control...

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Bibliografiska uppgifter
Huvudupphovsmän: Bosma, Madeleen, Hesselink, Matthijs K.C., Sparks, Lauren M., Timmers, Silvie, Ferraz, Maria João, Mattijssen, Frits, van Beurden, Denis, Schaart, Gert, de Baets, Marc H., Verheyen, Fons K., Kersten, Sander, Schrauwen, Patrick
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Diabetes Association 2012
Ämnen:
Metabolism
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478528/
https://ncbi.nlm.nih.gov/pubmed/22807032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1402
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