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Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement

Flavoproteins catalyze a diversity of fundamental redox reactions and are one of the most studied enzyme families(1,2). As monooxygenases, they are universally thought to control oxygenation by means of a peroxyflavin species that transfers a single atom of molecular oxygen to an organic substrate(1...

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Detalhes bibliográficos
Main Authors: Teufel, Robin, Miyanaga, Akimasa, Michaudel, Quentin, Stull, Frederick, Louie, Gordon, Noel, Joseph P., Baran, Phil S., Palfey, Bruce, Moore, Bradley S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844076/
https://ncbi.nlm.nih.gov/pubmed/24162851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12643
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