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One-pot Enzymatic Synthesis of Merochlorin A and B()
The polycyclic merochlorin A and B are complex halogenated meroterpenoid natural products with significant antibacterial activities that are produced by the marine bacterium Streptomyces sp. strain CNH-189. Here we employ heterologously produced enzymes and chemical synthesis to fully reconstitute t...
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| Veröffentlicht in: | Angew Chem Int Ed Engl |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4229033/ https://ncbi.nlm.nih.gov/pubmed/25115835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201405694 |
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