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One-pot Enzymatic Synthesis of Merochlorin A and B()

The polycyclic merochlorin A and B are complex halogenated meroterpenoid natural products with significant antibacterial activities that are produced by the marine bacterium Streptomyces sp. strain CNH-189. Here we employ heterologously produced enzymes and chemical synthesis to fully reconstitute t...

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Detaylı Bibliyografya
Yayımlandı:Angew Chem Int Ed Engl
Asıl Yazarlar: Teufel, Robin, Kaysser, Leonard, Villaume, Matthew T., Diethelm, Stefan, Carbullido, Mary K., Baran, Phil S., Moore, Bradley S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229033/
https://ncbi.nlm.nih.gov/pubmed/25115835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201405694
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